Impact of e cigarette vaping on the immune system across the body Physiological Reviews American Physiological Society A new study published in Nicotine & Tobacco Research found that those using e cigarettes alone were more than twice as likely to develop COPD than people who didn't use any tobacco products, E Cigarettes May Cause COPD. Here's Why Prince Court Medical Centre E Cigarettes And Copd E Cigarettes Are Not a Safe Alternative for COPD: A Closer Look