Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor