There's a reason L carnitine keeps showing up in PCOS research Because PCOS is closely tied to insulin resistance, inflammation, and metabolic dysfunctionand L carnitine plays a role in energy metabolism and fat utilization. Nutritional Supplements and Complementary Therapies in Polycystic Ovary Syndrome Advances in Nutrition Role of Oxidative Stress and Carnitine in PCOS Patients IntechOpen L carnitine is a naturally occurring amino acid structure that is made in the human brain, liver, and kidneys. L carnitine plays a critical role in energy production, as it converts fat into energy.