Spot the Dot! Growths on the lips are not too common. Clinically, this was consistent with a labial melanotic macule (aka freckle on the lip). These are benign growths which can be Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Pigmented macular lip lesion Clinical Advisor Oral Malignant Melanoma Oral Cancer Foundation Information and Resources about Oral Head and Neck Cancer