How To Give a Subcutaneous (SubQ or SQ) Injection OncoLink How To Give A Subcutaneous Injection And Sites The HCG Institute Are some methods of administering HRT inherently better than others? Audience requested: subcutaneous injections. Subcutaneous means under the skin. In this type of injection, a short needle is used to inject medication You can come see us every week if you want for weekly injections but we also teach you how to safely self injection , subq (fat tissue)injections if you prefer to do it at home!