Melanosis coli is dark brown black pigmentation of colorectal mucosa associated with chronic use of laxatives containing anthraquinone. Examples of such laxatives include senna and rhubarb derivatives. Clinical Importance: There is no association Melanosis coli: Harmless pigmentation? A case control retrospective study of 657 cases PLOS One Pathology Outlines Melanosis coli M79.1 ICD 10 Code: Myalgia
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