A Rare Case of Oral Mucosal Pigmentation: Differential Diagnosis and Case Presentation JCDA Oral melanotic macule Stock Image C067 2477 Science Photo Library Oral Melanoma: A Rare but Aggressive Oral Cancer Oral melanoma is a rare and highly aggressive malignant tumor that develops from melanocytes within the oral mucosa. It most commonly affects the Labial melanotic macule. B). Increased numbers of me lanocytes along Download Scientific Diagram