Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Correcting glucose 6 phosphate dehydrogenase deficiency with a small molecule activator Nature Communications G6PD Deficiency Medication Allergies: Safe Prescribing Guide for UK Patients Bolt Pharmacy G6PD Deficiency. Treatment with Our Supplements.