The role of ROS in exercise mediated WAT browning. Exercise causes oxidative stress in skeletal muscle and reduces the level of GSH. GSH provides electrons for glutathione peroxidase (GPXs), which eliminates H2O2. Reducing Glutathione peroxidase activity is neuroprotective in models of Huntington's disease Nature Genetics Non covalent interactions in the glutathione peroxidase active center and their influence on the enzyme activity Organic & Biomolecular Chemistry (RSC Publishing) Figure 1 from Comparing glutathione peroxidase and glutathione reductase activity and their associations with cardiovascular measures in Africans and Caucasians : the SABPA study Semantic Scholar