Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Acetaminophen, also known as Tylenol, is used to help with pain & to reduce fever. However, taking too much acetaminophen can be harmful to the liver which filters out toxins & Amazon.com: Designs for Health L Glutathione Power 1000mg Reduced L Glutathione Powder Supplement to Support Normal Detoxification Immune + Antioxidant Support Easy Mix in Drink Powder (50 Servings 50g) : Health & Household Tylenol depletes glutathione your liver's most important protective antioxidant. Every dose chips away at it. So instead of taking lower doses every 46 hours, I recommend spacing to 1000mg every 8 hours.