TYLENOL [Acetaminophen] metabolism A lot of GLUTATHIONE is needed to deal with the Oxidative Stress generated by the CYP 450 metabolism of Tylenol. When people go to the ER for Tylenol Overdose Frontiers MitochondrialLysosomal Axis in Acetaminophen Hepatotoxicity Paracetamol Induced Hepatotoxicity , Overdose NAPQI formation Glutathione depletion Liver cell necrosis. Early N acetylcysteine (NAC) can save the liver., #Pharmacology #mbbs #Hepatotoxicity File:Paracetamol metabolism.svg Wikimedia Commons
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glutathione depletion paracetamol The Metabolism of Acetaminophen and the Synthesis of Glutathione