Labial Melanotic Macules in Atopic Dermatitis: An Observational Study Semantic Scholar Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI In the process of removing a Labial Melanotic Macule. A Labial Melanotic Macule is a well defined, oval, brown to black, flat patch on the central third of the lower lip, as seen Lip Discoloration: Causes, Types, and Correction by Location La Bouche Parfaite