Benefits of Glutathione IV Fast Antioxidants Glutathione 500 mg Plus 21st Century Vitamins 21st Century Vitamins Should You Replace Vitamin C With Glutathione as You Age? As we get older, our skins antioxidant defense slows down so many people ask if they should swap Vitamin C for GlutathioneThe answer? Can you take glutathione without vitamin C? The simple answer: NO! Glutathione will not work without Vitamin C. Glutathione remains in two states, active and inactive. When it's in its active state,