Pigmented Lesions of the Oral Mucosa Pocket Dentistry PDF] Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis. Semantic Scholar Transformation of a benign oral pigmentation to primary oral melanoma Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in