Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst High Expression of G6PD Increases Doxorubicin Resistance in Triple Negative Breast Cancer Cells by Maintaining GSH Level Glucose 6 Phosphate Dehydrogenase Blister Cell in G6PD Deficiency , Red Blood Cell with a clear vacuole like area on its membrane, resembling a blister., It usually results when splenic macrophages remove precipitated Heinz