CJC 1295 Side Effects, Complications, and Risk Profile That popular CJC Ipamorelin combo? It's a common cause of histamine reactions. I've experienced it 3 times: fast nausea, itchy skin, and a full body flush within minutes. It felt scary, but each time, Peptide injections can sometimes cause redness or itching at the injection site, but most of the time this is not a true allergy. In the skin, we have mast cells that contain CJC 1295 Ipamorelin Injections Wellness at the Spa