There's a reason L carnitine keeps showing up in PCOS research Because PCOS is closely tied to insulin resistance, inflammation, and metabolic dysfunctionand L carnitine plays a role in energy metabolism and fat utilization. L Carnitine Shots: Boost Fat Loss, Energy & Metabolism! Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial eBioMedicine The Role of l Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation