Frontiers The effect of major depressive disorder comorbidity on ischemia modified albumin levels, a marker of oxidative stress, and antioxidant defense system in patients with obsessive compulsive disorder Your Glutathione Index Defines How Your Cells Are Ageing New research indicates a correlation between depression and reduced levels of antioxidants in the . Specifically, studies show that individuals with depression often exhibit lower levels of antioxidant enzymes like glutathione and Glutathione: Benefits and Supplements