The FDA Regulations say the minimum age to sell tobacco and vaping products is 18, but it may be different for your store. We Card Most E cigarette Users Ages 18 to 29 Never Smoked Before American Cancer Society E cigarette users U.S. by age Statista Just a reminder, the minimum age to buy nicotine products in Indiana is 21. This means retailers are prohibited from selling cigarettes, e liquids, and e cigarettes to anyone under age 21. We